The welfare of the entire ecosystem including that of the expanding universe is to be considered before any unnatural action is taken as its impact in future is beyond our comprehension

The study of the entirety of the expanding universe will give us take decisions on maintaining all existing systems of the universe function amicably.

What is the extent to which we can have a forethought?
Should every step of action we propose be changed to be pragmatic at any given point of time as we gain more knowledge?
What is the vicinity limitation to such perimeter of action in both three dimensions and the fourth dimension of space time?

If all systems keep functioning amicably why should there be any mutations or adaptations? These questions will be found an answer by thorough research